Source: The States Adjutant General's Report. Published by the Sate of Kentucky.

The 16th Kentucky Infantry was organized in December, 1861, at Camp Lee, near Maysville, Kentucky, under Colonel Charles A. Marshall, and was musterewd into the United States service on the 27th day of January, 1862, by Lieutenant George H. Burns, United States Mustering Officer. Before the thorough organization of the regiment, and, in fact, before muster into the United States service, it was ordered from Camp Lee to the Big Sandy, and participated in the battle of Ivy Mountain, losing many men in killed and wounded. After the battle of Ivy Mountain, it returned to Camp Lee and completed its organization, and was mustered into the United States service. It again returned to the Virginia border, under directions of General Nelson, where it remained untill July 1862, when orders were received to march to Covington, Kentucky. After a short stay at Covington, it proceeded to Louisville, Kentucky, and performed guard duty on the Nashville railroad until November, when ordered to Lebanon, Kentucky. It remained in the Southern portion of Kentucky during the winter of 1862, protecting the people and thoroughfare from the frequent invasions of guerrillas from Tennessee. It was ordered by General Burnside to accompany him on his East Tennessee campaign. The majority of the regiment veteranized in January, 1864. It has participated in the following named battles in which loss was sustained, viz: Ivy Mountain, Kentucky; Marrowbone, Kentucky; Kingston, Tennessee; Mossy Creek, Tennessee; Resaca, Georgia; and the numerous battles of the Atlanta campaign.

It is a matter of regret that the muster-out rolls of the non-veterans of this regiment are not on file in the Agjutant General's Office of Kentucky, from which a full military history of each officer and enlisted man might be given. The United States muster-in rolls of this command are also missing, and applications to Adjutant General's Office at Washington has failed to secure them. I am therefore compelled to substitute the State muster-in rolls in lieu thereof.